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Anti-inflammatory and antipyretic activities of Hemidesmus indicus root extract


K Lakshman
HN Shivaprasad
B Jaiprakash
S Mohan

Abstract

The methanolic extracts of Hemidesmus indicus (Asclepiadaceae) root (100, 200 and 400 mg/kg orally) were tested in carrageenan-induced rat paw oedema and brewer\'s yeast-induced pyrexia in rats to assess their anti-inflammatory and antipyretic activities respectively. The paw volumes and pyrexia in rats were reduced significantly (P<0.05) compared to that of control. These results indicate that the extracts possess anti-inflammatory and antipyretic properties.

Keywords: Hemidesmus Indicus, anti-inflammatory and antipyretic activity

African Journal of Traditional, Complementary and Alternative Medicines Vol. 3(1) 2006: 90-94

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eISSN: 0189-6016