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Hypoglycaemic activity of the leaves extracts of Bersama engleriana in rats


Georgette Nyah Njike
Pierre Watcho
Télesphore Benoît Nguelefack
Albert Kamanyi

Abstract

The hypoglycaemic properties of the aqueous and methanol extracts of the leaves of Bersama engleriana were evaluated in normoglycaemic rats in order to scientifically validate its traditional therapeutic use. With a dose of 300 mg/kg b.w. only the aqueous extract appeared to be significantly effective while at high dose, 600 mg/kg b.w., the aqueous and methanol extracts of Bersama engleriana reduced the blood glucose level by 37.7% and 49.11% after 8h of treatment of rats respectively. These results confirm the hypoglycaemic properties of some extracts of the leaves of Bersama engleriana with the aqueous extract appearing more active.

Key words: Bersama engleriana, hypoglycaemic effect, leaf extract

Afr. J. Trad. Comp. Alt. Med. Vol.2(3) 2005: 215 - 221

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eISSN: 0189-6016