Malignancy and rheumatic disorders: a review

Abstract

Background: Some malignancies may present or be associated with musculoskeletal manifestations. Additionally, therapies for malignancies can cause rheumatic disease syndromes.
Objective: The aim of this literature review is to address the various malignancies and their pharmacologic therapy that are associated with an increased risk of rheumatic disease.
Data source: The literature review uses medical science-based literature published locally and internationally on the risk of rheumatological diseases in patients with malignancies and the use of cancer chemotherapeutic agents.
Conclusion: Malignancies have been associated with a number of rheumatic manifestations either of the illness itself or as paraneoplastic syndromes. Similarly various rheumatological diseases may occur as a result of treatment.