Spontaneous vesicoureteral refl ux resolution in children: A ten-year single-centre experience

Abstract

Background/Aim: To evaluate the spontaneous resolution rate in infants and young children with vesicoureteral reflux (VUR).

Patients and Methods: Paediatric patients with VUR treated in our hospital from January 2000 to December 2010 were retrospectively analyzed. Only patients with pretreatment and followup voiding cystourethrogram were  included into the study. Treatment success was defined as complete
VUR resolution.

Results: The resolution rate for infants less than 1 year of age was 38.6% (17 of 44 renal units). Renal units with mild-moderate VUR (I-III) had a resolution rate of 40% (12 of 30 renal units) compared to 35.7% (5 of 14 renal units) with severe grade (IV-V) VUR. The resolution rate for children over 1 year of age was 39,1% (9 of 23 renal units). Renal units with mild-moderate VUR (I-III) had a resolution rate of 42.9% (9 of 21 renal  units) compared to 0% (0 of 2 renal units) with severe grade (IV-V) VUR.

Conclusion: Infants less than 1 year of age with nonsymptomatic, mild, moderate or severe VUR have a spontaneous resolution rate of more than 35% and therefore should receive a primary conservative therapy. Children over 1 year of age with nonsymptomatic mild-moderate VUR (I-III) have a
spontaneous resolution rate of about 40% and should receive primary  conservative treatment as well.

Keywords: Children, spontaneous resolution, vesicoureteral reflux