Knowledge, attitudes and practices related to isoniazid preventive therapy of adults living with HIV and AIDS in Berea district, Lesotho

Abstract

Isoniazid preventive therapy is an effective strategy for preventing tuberculosis in people living with HIV/AIDS. However, its uptake among this group is very low. Knowledge, attitudes and practice related to isoniazid preventive therapy may play a role regarding this poor uptake. The aim of this study was to assess and describe knowledge, attitudes and practices related to isoniazid preventive therapy of adults living with HIV in Berea district, Lesotho. Guided by the theory of planned behaviour, a quantitative, descriptive design was used which included questionnaire administraton to a group of conveniently selected participants (n=350). Results are presented as percentage positive scores leading to enhanced isoniazid uptake. Specifically, knowledge predicting isoniazid uptake was determined as behavioural beliefs (88.9%), normative beliefs (82.9%), control beliefs (0.3%) and subjective norms (69.0%). The knowledge component favoured and attitudes (78.6%) enhanced isoniazid uptake. Practice was reflected as intention (99.4%), actual behavioural control (98.0%) and behaviour (82.9%). The practice component showed a strong tendency for isoniazid uptake. Recommendations are aligned to the theory of planned behaviour and include health promotion, training, and community involvement.

Keywords: Isoniazid uptake, theory of planned behaviour, tuberculosis, Lesotho.