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POSSIBLE MYASTHENIA AND LEMS IN THE SAME PATIENT :CASE REPORT AND REVIEW OF THE LITERATURE


Vinod Bhagu Patel
Pierre Louise Alfred Bill
Ahmed Iqbal Bhigjee

Abstract

ABSTRACT

Myasthenia gravis (MG) together with Lambert-Eaton myasthenic syndrome (LEMS) in the same patient is rarely described. This is a case report of a patient who initially presented with myasthenia gravis and later complicated with presumably auto-immune LEMS. The patient was noted to be HIV positive. The interest lies in the behaviour of MG in immunocompromised patients and the electrophysiological changes at the neuromuscular junction in patients with both MG and LEMS. We present a patient who is HIV positive with a long history of MG and a possibly a more recent diagnosis of LEMS.

RESUME

L'association myasthénie et syndrome de Lambert-Eaton chez un patient est rarement décrit. Nous rapportons le cas d'un patient, VIH positif, s'étant présenté initialement par une myasthénie, complétée ultérieurement par un syndrome de Lambert Eaton vraisemblablement d'origine auto-immune et discutons les liens éventuels, au plan pathogénique.

Key words: Myasthenia Gravis, Lambert Eaton myasthenic syndrome, HIV, Myasthénie, syndrome de Lambert-Eaton, virus d'immunodéficience acquise, VIH

African Journal of Neurological Sciences Vol.23(2) 2004

Journal Identifiers


eISSN: 1015-8618
print ISSN: 1992-2647