Ap-PCR typing of carbapenem sensitive Pseudomonas aeruginosa iIsolated from clinical samples

Abstract

In this study the antibiotic susceptibility of 51 P. aeruginosa strains isolated from clinical samples were detected by the disc diffusion test. The susceptibility of P. aeruginosa strains were found as respectively 55% amicacin, 43% aztreonam, 75% netilmycin, 68% sefepim, 73% ceftazidim, 76% ciproflaxacin, 37% gentamicin, 84% meropenem, 76% piperasillin/tazobactam, 47% tobramycin and 84% imipenem. These results show that carbapenems are the most effective antibiotics for P. aeruginosa strains and the efficacy of meropenem and imipenem are high for P. aeruginosa strains Molecular typing profiles of 43 P. aeruginosa strains which are sensitive to meropenem and imipenem antibiotics with AP 1 primary were determined in AP-PCR. As a result of AP-PCR molecular typing study of this 43 P. aeruginosa isolate, no correlation was found out between antibiotic sensitivities and molecular types. This situation once again reveals that reasonable antibiotic usage in absolutely

African Journal of Clinical and Experimental Microbiology Vol. 9 (2) 2008 pp. 64-68