ANTIBIOTIC SUSCEPTIBILITY PATTERN AND MULTIPLE ANTIBIOTIC RESISTANCE INDEX OF PSEUDOMONAS AERUGINOSA URINE ISOLATES FROM A UNIVERSITY TEACHING HOSPITAL

Abstract

Urine samples submitted to the Medical Microbiology diagnostic laboratory of the Ahmadu Bello University Teaching Hospital, Zaria, were routinely screened for Pseudomonas aeruginosa over a three-month period with 13/150 (8.67%) of the pathogenic bacteria isolated positively identified. All the isolates were resistant to the cheap, commonly available antibiotics; rifampicin, ampicillin/cloxacillin, erythromycin, chloramphenicol and ampicillin but were uniformly susceptible to ciprofloxacin. The high prevalence of multidrug resistance indicates a serious need for broad-based, local antimicrobial resistance surveillance for continuous tracking of antibiotic resistance trends among all clinically relevant isolates and introduction of effective interventions to reduce multidrug resistance in such pathogens.


Key Words: Pseudomonas aeruginosa, antibiotic susceptibility, multiple antibiotic resistance, urinary tract infection


Afr. J. Clin. Exper. Microbiol. 2004; 5(2): 198 – 202.