Anti-inflammatory and Antipyretic Activities of Panicum Maximum

Abstract

Anti-inflammatory and antipyretic activities of leaf extract of Panicum maximum were evaluated to ascertain the folkloric claim of its use in fevers and inflammatory conditions. The crude leaf extract (48–144 mg/kg) of Panicum maximum was investigated for anti-inflammatory and antipyretic activities using various experimental models. The extract caused a significant (p<0.05 – 0.001) dose-dependent reduction in inflammation and fever induced by different agents used. The anti-inflammatory and antipyretic effects of this plant may in part be mediated through the secondary metabolites present in the plant.

Keywords: Panicum maximum, Anti-inflammatory, antipyretic