Anti-inflammatory and Analgesic activities of Methanolic Extracts of the Stem Bark of Alstonia Boneei, Ficus Elastica and Xylopia Aethiopica in Rodents

Abstract

The analgesic and anti-inflammatory properties of equimolar concentrations of the methanolic extracts of Alstonia Boneei (MEAB), Ficus Elastica (MEFE) and Xylopia Aethiopica (MEXA) were investigated in 0.1% acetic acid induced Pain (Writhing) in Mice , and 0.4ml of 0. 1% carrageenan induced inflammation in rats as a model of acute inflammation and compared with Indomethacin. The MEAB and MEXA at concentrations used did not produce significant or marked inflammatory and analgesic effects while MEFE significantly (p <0.05) inhibited carrageenan induced inflammation and acetic acid induced writhing.

Key Words: Analgesic, inflammation, Alstonia Boneei, Ficus Elastica and Xylopia Aethiopica, extracts