Evaluation of the inhibitory potentials of eight higher nigerian fungi against pathogenic microorganisms

Abstract

Studies were carried out to determine antimicrobial potentials of crude
and purified methanol extracts of some selected Nigerian mushrooms
against some selected pathogenic microorganisms. The best in vitro
antibacterial activity (24.0mm) was observed with the purified extract
(PRE) of Polyporus giganteus against E. coli. This was followed in
order by PRE of Pleurotus florida against K. pneumoniae with 22.0mm
(P < 0.05). Among the screened higher fungi, only the extracts of
Pleurotus tuber-regium, were able to inhibit the growth of P.
aeruginosa. It was also observed that antifungal activities of these
mushrooms were generally low. Candida albicans were inhibited by
the extracts of P. giganteus and T. robustus only while other fungi
produce no zone of inhibition The observed minimum inhibitory
concentration (MIC) of M. jodocodo against E. coli was 2.75mg/ml
while that of T. robustus against M. bourlardii was 15.75mg/ml. The
significance of these observations was discussed.
(Afr. J. Biomed. Res. 11:197 - 202)

Key Words; Antimicrobial, extraction, edible fungi, disease, microorganisms