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Navigating the landscape of pancreatic tumors: An in-depth analysis of classification methods.


Prakashini Koteshwar
T Visakh
Athira Rajeev
S Shailesh Nayak

Abstract

Pancreatic tumors are, oncological diseases, considered one of the toughest types of cancers due to their malignancy and unfavorable prognosis. This piece deals with the complexity of pancreatic tumor classification and the multidisciplinary approaches used to arrive at a comprehensive framework and personalized care. The histopathological classification is a starting point, but the development of molecular techniques and radiological techniques and their utilization expands the scope of considerations in clinical practice. Genomics testing allows for molecular classification of pancreatic ductal adenocarcinoma (PDAC) through the identification of discrete subtypes with varying therapeutic yields. Radiology in the process of adding radiomics to it, can highlight the tumor parameters from an objective point of view. IHC fuses the others and helps to generate the picture of protein expression patterns. Integration of comprehensive IHC markers with genomic profiling and machine learning enables better stratification accuracy and treatment individualization. With these strategies working hand-in-hand, the optimism is high that there will be better outcomes for pancreatic cancer patients through tailored treatment approaches. This refrains the significance of a coordinated effort involving many disciplines in the attempt to deal with the complexity of Pancreatic Cancer and treatment.


Journal Identifiers


eISSN: 1119-5096
print ISSN: 1119-5096