Evolutionary and emerging cosmos of Dengue infection in India

Abstract

Dengue is one of the most common vector disease in human which is endemic in more than 125 nations across the globe. It is endemic in most of the Indian states and with all the serotypes existing together. Studies on the nature of the dengue infection and its serotype and genotype has been studied regionally across India . The review attempts to discuss the evolution and emergence of Dengue virus systematically across India till 2022. The observation that DENV1 to DENV4 serotype co- existing make it more likely to mutate and serve as Reservoir for emergence of varied strain in India. Also the genetic modification with emerging of diverse genotype and lineage seems to preludes the severity of the infection. Thus those existing the southern region have extended to the norther region of India despite the difference in environment factors with formation of more resistant and virulent serotype/genotype mutant Virus.