K+-induced relaxation in vascular smooth muscle of alloxan-induced diabetic rats

Abstract

The effects of different concentration of intracellular potassium (K⁺), on rate of relaxation were studied in isolated aortae of normal and diabetic rats. The relaxation responses induced by raised extracellular potassium concentration was attenuated in aortic rings from diabetic rats. Possible reasons are discussed in the text.

Keywords: Smooth muscle, alloxan, diabetes, K⁺