Identification and antifungal activity of Streptomyces sp. S72 isolated from Lake Oubeira sediments in North- East of Algeria

Abstract

The aim of this study was to identify a new actinomycete isolate Streptomyces sp. S72 with antifungal activity from sediments of Oubeira’s Lake located at the North-East of Algeria. This isolate was identified based on a great variety of morphological, cultural, physiological and molecular characteristics analysis of 16S rDNA sequence. The test of antifungal activity for several pathogens fungi causing invasive aspergillosis and systemic candidiasis revealed that the Streptomyces sp. S72 was a good moderate antifungal compound producer against Aspergillus fumigatus and Candida albicans, and had no activity against Aspergillus flavus, Aspergillus niger, Candida pseudotropicalis and Candida tropicalis.

Key words: Streptomyces, Oubeira’s Lake, antifungal activity, Candida albicans, Aspergillus fumigatus.