Antibacterial activity of crude extracts from Mexican plants against methicillin-resistant Staphylococcus

Abstract

The aim of this study was to evaluate the antimicrobial activity of 36 extracts from 18 vegetal species used as soap, insecticides, insect repellent and for the treatment of several diseases likely associated to microorganisms. The vegetal species were collected in Oaxaca, Puebla and Veracruz States, México. The extracts were evaluated against isolates of nosocomial infections of Staphylococcus aureus and Staphylococcus coagulase negative resistant to Methicillin by a modificated agar diffusion method. The results demonstrate an important antibacterial effect in vitro, against all of the strains of Staphylococcus tested mainly with those from Vernonanthura oaxacana, Trixis silvatica, and with those of Perezia hebeclada. The minimum inhibitory concentration for V. oaxacana and P. hebeclada was 250 μg/disc and for T. silvatica it was 15 μg/disc. These extracts showed an important potential that would contribute to the development of new agents against infections by Staphylococcus.

Key words: Crude extracts, antimicrobial activity, intrahospitalary infections, methicillin-resistant Staphylococcus coagulase negative.