Antimicrobial efficacy and tissue reaction of Euphorbia hirta ethanolic extract oncanine wounds

Abstract

Antimicrobial efficacy and tissue reaction of crude ethanolic extract of Euphorbia hirta was investigated in canine infected incised wounds. The gross appearance and histopathological reactions of the lesions were evaluated at 72 h after treatment. The results showed that crude ethanolic extract of E. hirta neither promoted the growth of Staphylococcus aureus nor provoked tissue reaction in canine wounds. It was concluded that infected wound would benefit from treatment with ethanolic extract of E. hirta and its use in surgical site preparation is thus recommended.

Key words: Antimicrobial, efficacy, tissue reaction, Euphorbia hirta, canine wounds.