Isolation of antibacterial pentahydroxy flavones from the seeds of Mimusops elengi Linn

Abstract

In order to search for antimicrobial phytochemicals, two antibacterial compounds were detected from the seeds of Mimusops elengi Linn. The compounds were extracted by ethyl acetate and purified by
column chromatography. Their structures were elucidated through IR, 1H NMR and GC-EL-MS spectral analyses. After characterization, the compounds were identified as 2,3-dihyro-3,3’4’5,7- pentahydroxyflavone and 3,3’,4’,5,7-pentahydroxyflavone. The compounds showed strong inhibitory activity against Gram positive and Gram negative bacteria.