Advances in highly specific plant gene silencing by artificial miRNAs

Abstract

Endogenous microRNAs (miRNAs) are potent negative regulators of gene expression in plants and animals. Through artificially transformed miRNA (amiRNAs) to target one or several genes of interest is becoming a powerful tool for silencing genes. The characteristics and application prospect of artificial microRNA (amiRNA) technology were reviewed.

Keywords: Gene-silence, RNA interference, MiRNA, Artificial-microRNA