The effects of the seeds of Galeopsis ladanum on fattening performance in quails and occurrence of rhabdomyolysis in rats

Abstract

This study was conducted to investigate the effect of Galeopsis ladanum seeds on rhabdomyolysis occurrence in rats as an animal model and fattening performance of quails. Control group was fed with basal diet without G. ladanum seeds. Diets of treatment groups contained 2 or 4% of G. ladanum seeds, respectively. All animals, quails and rats were fed individually. At the end of the study, 2 and 4% of G. ladanum seeds in the diets did not have reverse effect on body weight, weight gain and feed intake in quails. Besides, treatment group one had a better feed conversion ratio at the end of the third week (p<0.05) and up to 28 days of age (p<0.05). At the end of the feeding period, quails were slaughtered and their drumsticks were fed to the rats either raw or grilled. After consumption of the meat, their serum and organs were subjected to biochemical and pathologic investigations. Although, no pathological finding was observed in the tissue samples, serum myoglobin and enzyme levels were found to be higher than that in the control group (p<0.01). Although, no pathological finding was observed in the tissue samples prepared from rats and quails for histopathological examination, the increase in serum myoglobin and enzyme levels may be due to subcellular changes in the target tissues of toxic substance.

Keywords: Galeopsis ladanum, performance, rhabdomyolysis, quail