Histogenesis of human foetal cerebellar cortex

Abstract

The objective of present study is to describe the prenatal histogenesis of human cerebellar cortex. The aim of this study is to demonstrate the various histological features of human foetal cerebellum in spontaneously aborted fetuses of different gestational ages for analyzing the cerebellar histology. Histogenesis of cerebellum is observed from 13 weeks to 36 weeks of gestational age by dividing the specimens into six gestational age groups (group A to group F). External granular layer is observed at 13 weeks of gestation and purkinje cell layer is arranged at 17 weeks as a multilayered and single layer at 36 weeks of gestation. The knowledge of cerebellar anatomy has a tremendous neurosurgical importance. Future investigations might involve evaluation of the cerebellum at other gestational ages.

Keywords: Cerebellum, Histogenesis, Purkinje cell