Goserelin inhibiting uptake on sodium pertechnetate Tc-99 mthyroid scan: A case report

Abstract

Introduction: Thyroiditis may be induced by goserelin (a long acting analogue of gonadotropin - releasing hormone) prescribed for the  treatment of pain and bleeding of endometriosis. Goserelin induced thyroiditis has a possibility of affecting thyroid function and hence may cause poor uptake on sodiumpertechnetate Tc-99m thyroid scan.

Case presentation: This case report highlights a rare instance of a middleaged woman with symptomatic toxic goitre whose sodium  pertechnetate Tc99m thyroid scan uptake was inhibited by goserelin therapy.

Conclusion: Medical personnel caring for patients on goserelin need to be aware of the possibility of it affecting thyroid function.