Main Article Content

Clinical and microbiological profile of adult inpatients with community acquired pneumonia in Ilorin, North Central, Nigeria


Olutobi Babatope Ojuawo
Olufemi Olumuyiwa Desalu
Ademola Emmanuel Fawibe
Ayotade Boluwatife Ojuawo
Adeniyi Olatunji Aladesanmi
Christopher Muyiwa Opeyemi
Mosunmoluwa Obafemi Adio
Abdulraheem Olayemi Jimoh
Dele Ohinoyi Amadu
Abayomi Fadeyi
Kazeem Alakija Salami

Abstract

Background: The optimal management of community acquired pneumonia (CAP) depends on the clinical and microbio- logical profile in the locality.


Objectives: To determine the clinical and microbiological profile of patients admitted with CAP in Ilorin, Nigeria.


Methods: One hundred and two consenting consecutively selected patients with clinical and radiologic confirmation of CAP were recruited in 12 months. The socio-demographic, physical examination and laboratory/radiologic parameters were documented in a questionnaire. Microbiological evaluation of their sputum was done and blood samples were taken for complete blood count, culture, serum urea and serological evaluation for atypical bacteria and some viral pathogens.


Results: CAP constituted 5.9% of the total medical admissions during the one-year study period. The mean age of the pa- tients was 49 ± 22 years with the largest frequency in those aged 65 years and above. The commonest symptoms were short- ness of breath (96.1%) and cough (94.1%), with a median duration of 3 days from symptom onset to admission. Systemic hypertension was the commonest comorbid illness (25/102; 24.5%). Klebsiella pneumoniae was the predominant pathogen iso- lated (20/102; 28.1%). The susceptible antibiotics were Imipenem, Ceftazidime and Ceftriaxone. Intra-hospital mortality was 17.6%. CURB – 65 score of ≥ 2 and the presence of complications of CAP were the independent predictors of mortality.


Conclusion: CAP constitutes a significant disease burden in Ilorin, Nigeria. Typical bacteria accounted for over half of the pathogens isolated from the patients with gram negative agents predominating. This highlights a possible shift in the micro- biological profile which could guide empirical treatment.


Keywords: Community acquired pneumonia; microbiological profile; Nigeria.


Journal Identifiers


eISSN: 1729-0503
print ISSN: 1680-6905