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An overview of Pneumocystis jirovecii pneumonia for the African generalist practitioner


I Govender
O M Maphasha
S Rangiah
C Steyn

Abstract

Introduction: Pneumocystis jirovecii is the causative organism of Pneumocystis pneumonia (PCP) in humans, which is more common among immunocompromised patients. Classically patients present with fever, non-productive cough, and dyspnoea. In the HIV-infected individuals the symptoms may be subtle at first, but gradually progress over several weeks. In the HIV-uninfected patient, however, the duration of symptoms is shorter and more severe, mainly due to the increased inflammatory response of the HIV-uninfected patient.
Methods: This article focuses on the diagnostic methods and then the management and prophylaxis principles of PCP by reviewing the best current practices and guidelines in Africa.
Conclusion: This overview is presented by clinicians who have experience with PCP and is directed mainly at first-line healthcare providers.

Keywords: Pneumocystis jirovecii pneumonia, african generalist practitioner.


Journal Identifiers


eISSN: 1729-0503
print ISSN: 1680-6905