The New Diagnostic Marker For Acute Pulmonary Embolism In Emergency Department; Mean Platelet Volume

Abstract

Objective: The aim of this study was to investigate the diagnostic importance of mean platelet volume (MPV) on acute pulmonary embolism (APE) in the emergency service (ED). Methods: Subjects were selected from patients admitted to ED with clinically suspected APE. Demographic, anthropometric and serologic data were collected for each patient. Results: A total of 315 consecutive patients were analyzed, including 150 patients (53.44 ± 15.14 y ; 92 men/58 women) in APE group and 165 patients (49.80 ±13.76y; 94 men/71 women) in the control group. MPV in the APE group was signifi cantly higher than in the control group (9.42±1.22 fl vs. 8.04±0.89 fl , p < 0.0001). The best cut-off values for MPV when predicting APE in patients with clinically suspected APE presenting at the ED were 8.55 fl (sensitivity 82.2%; specificity 52.3%). Conclusions: The present study described that MPV is helpful parameter for the diagnosis of APE in ED, for the first time in the literature. By the means of that a valuable parameter may be helped in early detection of APE in ED.

Keywords: Acute pulmonary embolisms, emergency department, mean platelet volume, thrombus

African Health sciences Vol 14 No. 1 March 2014