Multivariate Regression of Liver on Intestine of Mice: A Chemotherapeutic Evaluation of Plant Extracts

Abstract

Mice infected with 50 cercariae of Schistosoma mansoni in unequal group sizes were challenged with some doses of Zingiber officinale extracts, Cremophore and Praziquantel. Data were available for the number of male
and female parasites, weights of liver and intestine, and egg per gramme liver and intestine tissues. Using an analysis of covariance model, the effects
of the extracts and compound on intestine were predicted. The findings revealed, with the aid of likelihood-ratio statistic, a marked improvement in
the precision of the estimates of the effects on intestine when the liver was
taken into consideration.

Key Words: Shistosomiasis; Multivariate Regression; Likelihood-Ratio
Statistics.