Sero-Prevalence of Cytomegalovirus Infection among New -Born Babies in Benin City, Nigeria

Abstract

Aim: The aim of this study was to determine the seroprevalence of cytomegalovirus (CMV) infection in newborn babies in our environment and hence the suitability of cord blood for stem cell transplantation. Methodology: Cord blood sera of 212 babies in the labour room of the University of Benin Teaching Hospital (UBTH) Benin City were screened for cytomegalovirus IgM between the period of June 2010 and January2011. An antibody titre greater than 1:20 was regarded as positive. Permission was obtained from the UBTH ethical committee before commencement of this study.

Result: None of the 212 infants tested was seropositive for CMV IgM. Conclusion: Although the prevalence of cytomegalovirus infection may be high in the general population, it is very low in newborn babies in this community. Hence it is quite suitable for stem cell transplant as far as the possibility of transfer of CMV infection is concerned.

Key words: Cytomegalovirus Infection, Newborn Babies