Ten-year histopathological analysis of phylloides tumour in a tertiary hospital in Nigeria

Abstract

Objective: Phylloides Tumour, previously called cystosarcoma phyllodes is a rare fibroepithelialtum our. The aim of this study was to evaluate the basic clinical and morphological features of this tumour.
Materials and Method: All cases of histologically diagnosed phylloides tumours were retrospectively analysed over a ten year period.
Results: A total of 28 cases of phylloides tumour were seen over a 10 year period. Phylloides tumour accounted for 1.1% of all breast lesions. The age range was from 14 to 63 years with the mean age of 30.4 years. Two age frequency peaks were seen. The first peak was in the age range of 16 to 20 years and another peak in the age range of 36 to 40 years. The mean age for benign phylloides was 26.6years whereas the mean age for malignant phylloides was 56.6 years. Phylloides Tumour was found to occur on both sides of the breast equally with 14 on the right and 13 on the left. Out of the 28 cases of the phylloides tumour, 22 (78.6%) were classified as benign, 4 (14. 3%) as borderline and 2 (7.1%) as malignant. The average tumour size was 8cm in diameter.
Conclusion: Most cases of phylloides tumour are benign. However, the malignant potential is related to advancing age. Older patients should be managed with a higher index of suspicion for malignancy.