Main Article Content
Infectious mucocutaneous morbidity in haart experienced and haart naive patients in an urban hospital in southern Nigeria
Abstract
Background: Highly active anti-retroviral therapy (HAART) has been shown to reduce morbidity and, mortality in Human Immunodeficiency Virus (HIV) infected patients. There is paucity of information on the impact of HAART on the prevalence and types of infectious cutaneous morbidities in HIV patients especially in West Africa.
Aim: To determine the prevalence and types of Infectious mucocutaneous morbidities in HAART experienced and HAART naive patients in the University of Benin Teaching Hospital, Benin city Nigeria.
Methodology: This was a comparative cross sectional study that involved 330 HAART experienced patients and 330 HAART naive patients. The study subjects were examined for cutaneous morbidities. A p value of < 0.05 was considered statistically significant.
Results: The mean age for the HAART experienced and naïve groups were 42.39± 10.1yrs and 39.9±11.2yrs respectively. The median CD4 count of the HAART naive group was significantly lower than the HAART experienced group (275.5 cells/ulvs 487cells/ul: p=<0.001).The prevalence of infectious cutaneous morbidity was significantly higher in the HAART naive compared to the HAART experienced patients (19.1% vs 5.5%, P<0.01). The most common infectious dermatoses in both groups were oral candidiasis and herpes zoster which were significantly more common in the HAART naive HIV infected patients.
Conclusion: Infectious mucocutaneous morbidities were more common in the HAART naive than HAART experienced HIV infected patients.
Aim: To determine the prevalence and types of Infectious mucocutaneous morbidities in HAART experienced and HAART naive patients in the University of Benin Teaching Hospital, Benin city Nigeria.
Methodology: This was a comparative cross sectional study that involved 330 HAART experienced patients and 330 HAART naive patients. The study subjects were examined for cutaneous morbidities. A p value of < 0.05 was considered statistically significant.
Results: The mean age for the HAART experienced and naïve groups were 42.39± 10.1yrs and 39.9±11.2yrs respectively. The median CD4 count of the HAART naive group was significantly lower than the HAART experienced group (275.5 cells/ulvs 487cells/ul: p=<0.001).The prevalence of infectious cutaneous morbidity was significantly higher in the HAART naive compared to the HAART experienced patients (19.1% vs 5.5%, P<0.01). The most common infectious dermatoses in both groups were oral candidiasis and herpes zoster which were significantly more common in the HAART naive HIV infected patients.
Conclusion: Infectious mucocutaneous morbidities were more common in the HAART naive than HAART experienced HIV infected patients.
