Assessment of dyslipidemia in renal disease patients

Abstract

Dyslipidemia is elevation of plasma cholesterol, triglycerides (TGs), or both, or a low high density lipoprotein level that contributes to the development of atherosclerosis. Lipid pattern of renal disease patients were determined. One hundred volunteers were recruited for this study which comprised of sixty renal disease patients and forty apparently healthy individuals attending Irrua Specialist Teaching Hospital, Edo State. Total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL), low density lipoprotein (LDL) as well as very low density lipoprotein (VLDL) were evaluated using standard methods. Our results revealed higher total cholesterol, triglycerides, very low density lipoprotein and low density lipoprotein but lowered high density lipoprotein in renal disease patients. There was a gender difference observed in the distribution of lipid in the study population. It is therefore imperative to include lipid profile in the test menu of suspected renal impairment cases in order to detect early dyslipidemia that may result in atherosclerosis. We therefore advocate mandatory lipid profile check on renal disease patients.

Keywords: Dyslipidemia, renal disease, atherosclerosis, hypercholesterolemia, Irrua.