Assessment of glucose, triglycerides and insulin resistance in antiretroviral (ARV) naïve Human Immunodeficiency Virus (HIV) patients

Abstract

Background: Malnutrition remains a significant but intriguing consequence of Human immunodeficiency virus (HIV) infection. Besides factors such as decreased food intake and malabsorption, Human immunodeficiency virus infection is typically associated with adverse metabolic events.

Aim: We examine the glucose; triglycerides as well as insulin resistance of HIV infected naïve subjects in Irrua.

Methods: A total of One hundred (100) HIV seropositive subjects and fifty (50) HIV seronegative individuals within the age range of 20-47 years as controls were enrolled into the study. Fasting Blood Sugar, Serum triglycerides as well as Insulin Resistance were evaluated using standard biochemical methods.

Results: Our results show increased glucose and triglycerides in HIV infected subjects but there was no significant differences observed in their mean values. The Insulin Resistance Index was below the cutoff value in both HIV infected and controls.

Conclusion: Glucose and Triglycerides may not be good markers of HIV disease progression.

Keywords: Assessment, Glucose, Insulin Resistance, HIV, Irrua