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Iodine Excess is a Risk Factor for Goiter Formation
Abstract
Background: Goiters have been associated with iodine deficiency. Although universal salt iodization in Uganda achieved a household coverage of 95%
by 2005, goiter rates are still high. This study investigated the association between iodine excess and goiter.
Methods: In a case control study, urinary iodine levels, complete blood count, T3, T4 and TSH levels were determined.
Results: We recruited, 60 goiter and 63 non goiter patients. The median urine iodine level for goiter patients was significantly higher than in non-goiter controls. Urinary iodine excretion was sufficient in 43%, more than sufficient in 31% and excess in 10% of cases. There was an association between excess urinary iodine levels and goiter.
Conclusion: Urinary iodine excess was significantly associated with occurrence of goiter.
Key Words: Iodine excess, Goiter, Sub Saharan Africa