Pathogens and risk factors for umbilical venous catheter-related infection in neonatal intensive care units: a scoping review

Abstract

Summary

Context and objective. Umbilical vein catheterization is an invasive procedure performed in neonates. The objective was to provide a synthesis of the existing evidence on umbilical venous catheter (UVC)-related infection by world regions. Methods. Scoping review following five phases developed by Arksey and O'Malley, improved in six phases to identify the research question, relevant studies, select studies, plot data, collate, summarize and report results including expert opinion. Results. Of 13 included studies, the incidence of UVC-related infections was higher in the African (38/1000 UVC days) and Asian (13.6/1000 UVC days) regions. Coagulase-negative Staphylococcus was predominantly responsible for Central Line-Associated Bloodstream Infection (CLABSI) in all regions except Africa where Klebsiella pneumoniae predominated. Device-related factor including KT stay time greater than 7 days was implicated in the occurrence of CLABSI in the Americas, Asia, Oceania regions. The combination of patient-related and device-related factors was implicated in Africa and Europe. Conclusion. Preventive measures for neonatal infections with adequate equipment would reduce the incidence of UVC-related infections in our settings.

Received: September 10^th, 2024

Accepted: January 22^th, 2025

https://dx.doi.org/10.4314/aamed.v18i2.7