One-pot synthesis of spiroglycol

Abstract

The synthesis of spiroglycol by one-pot reaction was studied using pentaerythritol, isobutyraldehyde and formaldehyde as starting materials. Under the optimum reacting conditions, the yield and purity of product were 93.6 % and 99.0 %, respectively. Compared to the synthesis methods reported in literatures, not only was the yield of product improved, but also two operating units were omitted. The product was characterized by ¹H NMR and IR.

KEY WORDS: One-pot synthesis, Spiroglycol, Pentaerythritol

Bull. Chem. Soc. Ethiop. 2008, 22(1), 149-152.