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PCl5 as a mild and efficient catalyst for the synthesis of bis(indolyl)methanes and di-bis(indolyl)methanes


Alireza Hasaninejad
Abdolkarim Zare
Hashem Sharghi
Reza Khalifeh
Ahmad Reza Moosavi Zare

Abstract

Phosphorus pentachloride (PCl5) can efficiently catalyze the condensation of indoles with aldehydes as well as ketones at room temperature to afford bis(indolyl)methanes and di-bis(indolyl)methanes in high yields and short reaction times.

 

KEY WORDS: PCl5, bis(Indolyl)methane, di-bis(Indolyl)methane, Indole, Aldehyde, Ketone

 

 

Bull. Chem. Soc. Ethiop. 2008, 22(3), 453-458.


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eISSN: 1726-801X
print ISSN: 1011-3924